You need
high-quality genomic data.

We know how to produce it.

The LSMC platform leverages the most advanced combination of long- and short-read sequencing technologies to produce the highest-quality raw sequence data at the best cost.

A scanned page of a research article from Genome Research journal titled 'The additional diagnostic yield of long-read sequencing in undiagnosed rare diseases' by Giulia F. Del Gobbo and Kym M. Boycott.
Scientific research article titled 'Long-read genome sequencing and variant reanalysis increase diagnostic yield in neurodevelopmental disorders' from 'Genome Research'. The page contains the article's abstract, author information, publication details, and a footer with publishing credits.
The cover page of a scientific journal article titled "Long read sequencing on its way to the routine diagnostics of genetic diseases," with details about the authors, publication date, and journal, Frontiers in Genetics.

Built-in clinical confirmation

Clinical standards require confirming reported variants using orthogonal technologies. By using a hybrid long- and short-read approach, LSMC offers built-in confirmation, eliminating costly auxiliary assays and extended turnaround times.

Adding long-read sequencing delivers 20% greater diagnostic yield with every sample, thanks to significantly richer data:

  • Difficult regions
    Coverage of previously difficult or inaccessible regions of the genome

  • Structural variants
    Short-reads alone miss large rearrangements

  • Methylation
    Long-reads reveal more than just the four bases of DNA. Direct methylation allows a deeper layer of biological understanding and assay development to be built on our platform.

Designed for clinical delivery

LSMC was purpose-built to support clinical diagnostics companies and large aggregators by a team accustomed to operations processing millions of samples per year. Using advanced automation and hard-won experience, the LSMC knows how to overcome the challenges and ensure you get the data you need, when you need it.

Ready to focus on biology,
not operations?